CD8 killer cells, which kill infected cells via apoptosis, are reduced in lymphopenia, forcing reliance on more inflammatory innate immune cells like macrophages.

“primarily the cd8 killer cells and so those cd8 killer cells can actually kill in a silent apoptotic way and when you get a reduction in those cells now you're you have to rely on the more inflammatory killing of the innate immune system like the uh white blood cells right which are much more inflammatory killing macrophages”