Prior probabilities from genomics and family history personalize the utility of screening tools and diagnostic power of tests.

“which is almost certainly going to become standard which is the utility of the genomics and family history which is you know genomics tells part of that story but it doesn't tell you what happened with your ancestors it's family history remains an incredibly important but you'll you'll start when a baby's born with a whole genome and a family history and that will generate for you the prior probabilities of different diseases being the diseases that afflict that person in the rest of their life”