Paul Saladino· MD
hypothyroidism and primary hyperoxaluria type one and they're looking at four patients three months to 23 years end-stage renal disease symptomatic hypothyroidism which is actually a great segue to yet another problem with oxalates or at least a potential issue in terms of excess deposition of oxalate in the thyroid so i want to talk a little bit about that i remember you and i talked a while ago about this autopsy series of patients well back in the 1970s there was a series of rat studies done shown that oxalate causes hypothyroidism and glandular under functioning generally so the gonads all these endocrine glands that produce hormones and so on to help run your body can get uh in trouble functionally unable to produce enough of the enzymes that you need for reproduction for maintenance of a healthy uterus for you know fertility and your your growth hormones and especially the thyroid glands