A clinically detectable cancer typically consists of about one billion cells, and liquid biopsies are the only current method to detect cancer below this threshold.

“one of the things that really is interesting is just how many cancer cells you need to actually even be detected right it's about a billion cells in a centimeter cubed so usually the number that's used yeah you couldn't even there's no clinical outside of what we now have as liquid biopsies there's no clinical way to even detect cancer shy of about a billion cells”