A study that is underpowered to detect a meaningful effect size is 'dead on arrival' and requires design changes or increased funding. — Whalespan
A study that is underpowered to detect a meaningful effect size is 'dead on arrival' and requires design changes or increased funding.
⚠ High risk
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
◐PARTIALLYSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“your your study is powered to detect like a a 70 difference in in all cause mortality in some you know they might be pointing something out that basically it's saying your study's Dead on Arrival if you actually run it this way right because there's no way you're going to see an effect size greater than 30 percent and yet you're only powered to detect it if it's 70 which is crazy”