Mice lacking a vitamin D receptor exhibit a progeria-like phenotype by eight months of age, including hair loss and wrinkled skin.

“And then at eight months, that mouse looks like a progeria. I mean, it doesn't even look like a two and a half year old mouse would normally look. It looks like some sort of progeria kind of phenotype where there's no hair, the skin is all wrinkled, their organs are all, like, shutting down.”