Peter Attia· MD
And then the idea, the observation that phosphorylation could be stimulated by various GPCR pathways and growth factor pathways got people thinking about what it might be doing.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And then the idea, the observation that phosphorylation could be stimulated by various GPCR pathways and growth factor pathways got people thinking about what it might be doing.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And then the breakthrough paper showed that, in fact, when cells are stimulated with certain growth factors, like EGF, or a certain subset of GPCR activators... And those stand for... G-protein coupled receptors. And EGF just for folks. Epidermal growth factor. Okay, so all growth. So these signaling pathways would activate the hydrolis of that lipid that the inositol 1,4,5-trisphosphate that comes