Peter Attia· MD
It's not to poo-poo clinical trials. It's just to acknowledge that clinical trials give us great information on averages, and the larger and more robust the trial, generally the more heterogeneous the data.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
It's not to poo-poo clinical trials. It's just to acknowledge that clinical trials give us great information on averages, and the larger and more robust the trial, generally the more heterogeneous the data.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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