Luminal type prostate tumors are exquisitely sensitive to testosterone suppression and less likely to metastasize compared to basal cell tumors.

“because it's it's if it if think about is on the basil side no if it's a luminal if it's a luminal type tumor think about it it's more dependent on that testosterone Rich micro environment with the DHT around it doesn't do as well theoretically living in the bone marrow when it metastasizes to the Bone or in the lymph nodes”

“the basil cells the cells that survive the drought the cells that survive in the absence of effect acely any testosterone at at all those are the ones that form more basilike tumors which are very very aggressive okay”

“so this is kind of a great tragedy it means that the cancers the prostate cancers that are most likely to kill you which by definition are the ones that spread are also the most capable of thriving in a low testosterone environment and therefore are least hurt by Androgen deprivation yes”