Cancer cells regulate mitochondrial biogenesis through nuclear genome programs and transcription factors.

“it turns out that not only the function of mitochondria but also just like the the production of mitochondria so mitochondrial biogenesis it's called like there's many different mitochondria or many many mitochondria per cell different cell types you know need different numbers of them based on their metabolic demands so cancer cells will actually regulate you know the amount of mitochondria they have — through these outside of mitochondria — programs if you will — transcription factors in many cases that regulate you know kind of the the program in the genome this is the nuclear genome not the mitochondrial genome that regulate this process”