Capsule-based Fecal Microbiota Transplantation (FMT) is effective but less so than enema-based delivery, likely due to loss of microbial diversity during processing.

“well I think people are still using the methodology of actually going up through the colon but but but people have tried to create more um uh you know they tried to create capsules and and try to be able to make it so that you can just drink these capsu you can sorry uh consume these cap capsules with a drink and then it gets there and and those seem to be effective they're they're not as effective as when you just the the enema um the enema version um and it's and because probably in the in the process of kind of getting that um stool into a freeze-dried format or into a pill format you're losing probably some of the diversity that you just get when you do it the the oldfashioned way”