Androgen deprivation therapy is a standard of care for high-risk prostate cancer, often concurrently with radiation.

“androgen deprivation for high-risisk disease is certainly standard of care uh Gleason 8 or higher for sure the Gleason 7s are always a a sort of a gray zone and so a 4 plus three with high volume disease typically also do get concurrent and adgiuant androgen suppression along with radiation”