Modern microbiomes are significantly less diverse than those of ancestral populations, making individuals more susceptible to the metabolic effects of sugar.

“so you know when you think about kind of tribes that you know honey and um you know berries for instance you don't get that all that often in nature you don't find it's something that you come across here and there so these kind of foods were relatively rare but the people could could eat them because they had these diverse microbiomes and it didn't really affect them metabolically”