A drug starting as late as middle age (between 20-60) can still provide a full lifespan benefit.

“that it sort of opened up what we now consider to be routine which is that you can actually have an impact on longevity and some at least some metrics of Health span when you start treatment in middle age and as we have started as a field to think about translational application that becomes hugely important because suddenly we're talking about treating middle-aged dogs or middle-aged people as opposed to trying to treat puppies and teenagers and that's just much more atic and practical from from the perspective of actually being able to implement”