T-cell receptors can be cloned and isolated to genetically modify lymphocytes to recognize specific driver antigens like p53, enabling them to attack cancer.

“and in fact now because we know the exact t- cell receptor sequences that we've cloned and isolated we it's almost an engineering problem because since we know the receptors we've now isolated libraries of receptors against p-53 K uh that we can now use to genetically modify lymphocytes to turn a normal lymphocyte that can attack the cancer and we have our first example of that now that we've submitted for publication targeting p53 by genetically altering a lymphocyte uh by giving it a receptor that could recognize some of these driver antigens”