Peter Attia· MD
I think what's missing I think what would give all of us a lot more confidence is if we had a mechanistic connection to the specific methylation changes and some cause of Aging or age related disease
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
I think what's missing I think what would give all of us a lot more confidence is if we had a mechanistic connection to the specific methylation changes and some cause of Aging or age related disease
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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but I would say, even if it's not what some people might consider the central driver, as long as it's picking up things that are critical to aging and you can use that to track aging or understand it a little bit better, I think it still has utility. I don't know if it needs to be kind of the central cause of aging for it to be useful.