Radiation therapy for large breast cancer can cause lung inflammation and secondary skin cancers.

“then that's where you start talking about doing more extensive radiation to the chest wall the regional lymph nodes sometimes even the internal mamory nodes and there while they can still spare the vast majority of the heart um it becomes a little trickier to fully avoid the heart there is a risk of so-called pentis uh inflammation of the lung from some of the radiation scatter there is a risk of secondary skin cancers which you can rarely see after the radiation”