Using paired t-tests with subtraction or difference analysis in radiology can make subtle changes more obvious and simple to detect.

“paired t-tests seems to be an easier problem to solve and an important problem to solve because a lot of times for us as radiologists like those those studies we still do things the same way when we review them whereas when you actually go and you take like a paired t-tests like you said and you actually do a subtraction or where you're looking for the difference or that Delta it can actually stand out and become very very simple and very obvious and once that subtraction is done”