Paul Saladino· MD
so say a 30 healthy 34 year old might have a level of 44 there nad I'm not sure what the units are but by the time you get to 80 most eight-year-olds are was below one below one
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
so say a 30 healthy 34 year old might have a level of 44 there nad I'm not sure what the units are but by the time you get to 80 most eight-year-olds are was below one below one
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And so my levels probably are half what they were when I was 20, scary thought. So my sirtuins are working maybe half as well as they did telling the troops to go out and fix my body.
unfortunately nad becomes depleted across various tissues including the brain as we age the brain skeletal muscle the heart these are all tissues with a very high metabolic demand and thus require a lot of nad
specifically the reduction of nad levels commonly observed in aging is thought to be a combination of decreased synthesis and recycling as well as increased consumption and degradation