The predictive value of acute ketamine response (e.g., dissociation) for long-term therapeutic effects is debated within the field, with some studies showing a correlation and others not.

“the field is pretty divided so the way that the acute effects have typically been measured is with a scale called the clinician-administered dissociative state scale which basically looks at dissociation but it was designed to look at dissociation from people having flashbacks from traumatic experiences and so it are some questions that are relevant for catamaran but some are not so it's like things moving in slow motion have colors change um do you have a sense of forgetting chunks of what have happened a lot of it is relevant but people have looked at other aspects of the acute experience so with these dissociative effects some studies i'd say about 25 find they project predict the therapeutic effects we've actually done a systematic review on this um but the others don't”