Replicative senescence is related to epigenetic clocks, but radiation-induced senescence is not.

“the relationship between senescence and epigenetic age is complicated because when it comes to inducing senescence there are several ways of inducing senescence one is simply what is known as replicatives replicative senescence you passage cells you split them and let them grow and grow and grow and that form of senescence is somewhat related to epigenetic clocks you know then there are other forms so-called radiation-induced senescence you radiate the cell and that form of senescence doesn't seem to accelerate the epigenetic clocks you know so it's complicated”