Peter Attia· MD
In many ways, mTORC2 is less important than mTORC1. I mean, you can modulate it more and still survive more.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
In many ways, mTORC2 is less important than mTORC1. I mean, you can modulate it more and still survive more.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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is it safe to say that most of the inhibition of mtor complex 2 seems to produce things that are not really desirable at all whereas the output of an mtor complex one inhibition pathway seems quite desirable at least sometime yes and in fact most genetic experiments have supported that conclusion