There is a significant problem with misdiagnosed and undiagnosed patients, with networks like the Undiagnosed Network seeing thousands of such cases annually.

“we have such an epidemic of misdiagnosis and undiagnosed patients part of my background that uh just mentioned briefly I'm the principal investigator of something of the coordinating Center of something called the undiagnosed Network it's a network with 12 academic hospitals going down the West Coast from University Washington Stanford you CLA to Baylor up the East Coast Harvard hospitals NIH and we see a few thousand patients every year and these are patients who have been undiagnosed and they were in pain”