Paul Saladino· MD
ApoE4 is actually protective for that actually helps does a huge number of things modulating the immune system modulating the immune response and it seems to be beneficial in that setting so it may have been a survival advantage due to the its effects on the immune system however when we then start talking about dementia at OE for is probably what you know is one of the few real genetic risk factors for dementia that we actually we can take seriously