Paul Saladino· MD
we don't there's no test that i'm aware of that's a great proxy for mtor activation in the blood
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
we don't there's no test that i'm aware of that's a great proxy for mtor activation in the blood
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
For example, it would be really great if there is a way in the blood to measure the activity of mTOR. We don't have that. It would also be great if we could measure other growth pathways like the RAS pathway without having to rely on tissue biopsies and things like that.