A 2018 case involved editing human embryos to confer HIV immunity by mutating the CCR5 gene, resulting in mosaicism and scientific backlash.

“so so so there was a there was a couple uh who wanted to have children the father was HIV positive and so they wanted to make sure that their uh children are not hi are not infected by HIV and and so so scientists uh made a mutation uh in the embryos uh that is a gene in called called ccr5”