The microbiome's complexity and translation from animal models to humans are complicated by diet, making animal models less predictive.

“and the microbiome is even worse because animals eat different foods your diet is one of the biggest things that impact your microbiome and so now you're saying you know what is an animal's microbiome how does it interact with the host and then you know what implications that I have for health so even one more step remov so um there are a lot of strains that exist you know from from Mouse to man but I think again because it's context it's not totally clear that you can really use these animal models to predict what will happen in a human”