Evidence suggests Lp(a) particles may enter and be retained in the subendothelial space, trigger inflammatory responses, and have a prothrombotic component, contributing to atherosclerosis risk.

“I suspect that it's both its ability but it's probably on all of the above when it comes to I meaning its are these particles more likely to enter the southern ethereal space I don't know why that would be the case are they more likely to be retained probably because they have that whole big Kringle oxidized moiety thing there are they more likely to kick off an inflammatory response very likely because of what they're dragging in with them and then on top of that to have the prothrombotic component I suspect is what's driving the increase in the risk of atherosclerosis”