Lp(a) particles may traffic oxidized lipid moieties into the arterial wall, stimulating inflammation.

“so we thought well maybe there's something happening in the particle maybe they have more oxidized phospholipids maybe they have different proteins so we've studied that and we we realized that these uh patients might have more cell adhesion molecules that are transported by lpa which make them more quote unquote sticky to endothelial cells or or fibrin clots or whatever they would make them or me maybe even macrophages because patients with high lpa also have”