Nine environmental factors contribute to metabolic dysfunction: diet, lack of sleep, sedentary behavior, chronic stress, environmental toxins, circadian disruption from light, lack of thermal stimuli, microbiome issues, and overuse of medications.

“it's our diet okay it's our lack of sleep it's our incredibly sedentary Behavior it's chronic stress so psychological stress and poor emotional health it is environmental toxins it is our modern relationship with light so circadian see or circadian disruption based on our new relationship with sunlight and artificial light it's issues with how we relate to temperature um so the fact that we live a Thermon neutral existence now we're all at 72 degrees and we don't have thermal stimuli to promote metabolic health and certainly microbiome issues which is kind of tied to food but also separate from food because there's a lot of other things destroying our microbiome and lastly it's the medications we're taking it's the it's the total and utter overuse of over-the-counter and prescription medications many of which directly cause mitochondrial dysfunction oxidative stress”