Grief is unremediated sadness causing persistent activity in the dorsal anterior cingulate cortex.

“what happens for example in grief grief is is unremediated sadness and the reason is because your brain is saying you know make this separation go away and you can't because other person is permanently gone as AKA dead or divorced or whatever it happens to be and so the grief is just this pulsating activity in the dorsal interior singulate cortex of the brain saying I must be reunited with that person but I can't be”

“But what happens, for example, in grief, grief is unreiated sadness. And the reason is because your brain is saying, "Make this separation go away." and you can't because the other person is permanently gone aka dead or divorced or whatever it happens to be.”