Rhonda Patrick· PhD
A lot of VPFC activity with low serotonin in the syninnapse is the same thing when people are falling in love. When they fall in love, there's a big dip in serotonin. It looks like clinical depression, as a matter of fact.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
A lot of VPFC activity with low serotonin in the syninnapse is the same thing when people are falling in love. When they fall in love, there's a big dip in serotonin. It looks like clinical depression, as a matter of fact.
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These are people who feel very strongly negative emotions. fear, anger, disgust, especially sadness, and they feel positive emotions at a very low simmer. These people tend to be very uh creative. And part of that is there's interesting research on the vententralateral prefrontal cortex, which is the part of the brain that's involved in rumination.