Consuming psilocybin mushrooms annually in college, with haphazard dosing and no controls, led to a perceived 'reboot' that removed anxiety and depression for extended periods.

“I experienced what I began to refer to as a reboot and I would have this anxiety and depression plaguing me I would go very very deep and looking back now I was almost certainly consuming minimum of five grams I'm sure I was consuming quite a high dose of mushrooms which is for those people who might read the the writing or listen to some of the presentations of someone named Terence Mckenna five grams is referred to as a heroic dose and that is a dose sufficient to flatten even the most resistant ego I believe is the wording that was used in any case I felt this decrease or even complete removal of depression anxiety that extended far beyond the supposed duration of effect let's just call it five to eight hours and there would be this afterglow period that certainly lasted most acutely for a day or two after the experience”