Atherosclerosis is associated with four primary factors: metabolism, lipoproteins, inflammation, and endothelial function.

“there are sort of four things that are out of whack when you're getting atherosclerosis and there are therefore obviously an you know an infinite number of combinations given how multivariate each of those things are but you know sort of if metabolism is out of whack if lipoproteins are out of whack if inflammation is out of whack if the endothelium is not functioning well”