Paul Saladino· MD
the the ratio and the amount of hdl cholesterol indicative of underlying metabolic dysfunction is clearly a determinant here of the amount of ischemic heart disease
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the the ratio and the amount of hdl cholesterol indicative of underlying metabolic dysfunction is clearly a determinant here of the amount of ischemic heart disease
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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low hdl is indicative of underlying metabolic dysfunction and when you have underlying metabolic dysfunction your relative risk of ihd goes way up