Caloric restriction may decrease energy metabolism more than expected based on body weight alone.

“we're going to write a grant there was it was a seven-year Grant the first two years which was you do a study show us that you can recruit people and maintain them in C restriction and they have to be not obese they can be overweight and the second is from the three chosen group we're going to design one study and it's going to be a two-year intervention and the first uh study uh we decided was basically to test if caloric restriction decrease your energy metabolism more than what you would expect on the basis of the body weight”