Peter Attia· MD
let's say that you are a young person when you're young this enzyme is really not present in the liver once you're eating sugar though if you eat a lot of sugar it will induce that enzyme
Loading…
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
let's say that you are a young person when you're young this enzyme is really not present in the liver once you're eating sugar though if you eat a lot of sugar it will induce that enzyme
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
sugar itself it looks like the induction of this enzyme probably would be reversible within a few weeks but once your uric acid goes up that will keep it elevated
meaning if you give a person allopurinol and you knock their uric acid from seven to four and make no other change do you reduce the conversion of glucose to sorbitol
so the the rate limiting enzyme is the enzyme that converts glucose to sorbitol and that enzyme's called aldos reductase and uh it's normally low in the liver but it gets induced and it can be induced by high glucose it's induced by high uric acid