Paul Saladino· MD
Stratifying the connection between "high cholesterol" and heart disease risk by insulin sensitivity clearly shows that metabolic health means everything here.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Stratifying the connection between "high cholesterol" and heart disease risk by insulin sensitivity clearly shows that metabolic health means everything here.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
make sure that your doctor is not just myopically focused on your LDL look at HDL look at triglycerides get an NMR panel look at small dense LDL even better yet something we talked about on the last podcast that hasn't come up on this one get a panel from Boston Heart looking at oxidized phospholipids on apob or yeah and get an hscrp get a fasting insulin get a fast ing insulin
you have to think of your whole lipid panel you can look at triglycerides and HDL but then in the work that I've done I've urge people to also look at their fasting insulin right because that's probably the best metric of your metabolic health