Peter Attia· MD
at least comparing a relatively clean standard American diet to a ketogenic diet it'd be hard to make the case that there was more than 50 to 150 calorie difference in energy expenditure at an isocaloric swap
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
at least comparing a relatively clean standard American diet to a ketogenic diet it'd be hard to make the case that there was more than 50 to 150 calorie difference in energy expenditure at an isocaloric swap
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it was really designed to be the study to work out the kinks to do the enormous study that actually never got funded but it was still a very good study and it still answered an important question which was at least comparing a relatively clean standard american diet to a ketogenic diet it'd be hard to make the case that there was more than 50 to 150 calorie difference in energy expenditure at an iso caloric swap
now was that a significant physiological increase I mean we can argue about that you know when when we talk about metabolic adaptation because people are talking about that now we always say we need at least 150 calories in the study we achiev statistical significance but it was just above 100 calories per day