Paul Saladino· MD
many of them had gained the weight back almost all of them had and many of them had gained more weight
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
many of them had gained the weight back almost all of them had and many of them had gained more weight
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the really scary thing is i think uh from that study is it was such a severe event that even six years later when kevin followed up with these guys they still saw metabolic suppression right they resonate blockers are still low because their bodies are still kind of you know in that kind of starvation mode where they've reduced metabolic rates
if you drastically cut calories like they did in the biggest losers so the biggest losers tv show or if you don't know about it people who are have severe obesity um show up and they basically are in a boot camp kind of thing situation for a couple months and they exercise like crazy and they get their diets are severely restricted and uh yeah and they lose weight pretty rapidly but what happens is their metabolic rates their bodies actually kind of put on the brakes and go into starvation mode and if you measure the resting metabolic rates uh they're they're crash right there their resin metabolic rates are way way lower