Metabolic health, specifically insulin sensitivity and metabolic flexibility, significantly impacts brain function due to the brain's high metabolic demand.

“the second one is metabolic health so you know if you think about it this way which is think of the fact that the brain this tiny organ people have heard me say this before roughly 2% of your body weight and yet approximately 20% of your metabolic demand so if you think about that enormous asymmetry it tells you that anything that plays a role in fuel partitioning and energetics is going to have an outsized impact on your brain and all of that points towards having remarkable fuel partitioning being very insulin sensitive and being very metab olic Al flexible”