The clearance of ApoB particles from plasma is regulated by LDL receptors on the liver.

“so scientifically we have to zero in on what regulates clearance of these particles and the simplest thing is to say well the only way these apob particles get cleared is our liver produces something called an LDL receptor which migrates to the surface of the liver cell that interacts with the blood flow the plasma and these LDL receptors are Engineers to recognize any apob peptide that floats by it so if an LDL particle containing apob floats by an LDL receptor it will get grabbed and then it gets internalized into the LDL receptor there and it getss catabolized”