Metabolic pathways tend to maintain their current state, with intermediates from one pathway inhibiting another.

“that physiology gets going it has momentum we know that when you're burning fat and doing beta oxidation there is a tendency to want to continue doing that many of the products of that citrate etc sort of inhibit pyruvate dehydrogenase on the other side of the biochemistry and vice versa is also true when you're doing glucose based metabolism there are intermediates that inhibit beta oxidation and carnitine promote oil transferase at the level of mitochondria”