Paul Saladino· MD
blocking the cb1 receptor results in better metabolic profiles i think satiety has a lot to do with this
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
blocking the cb1 receptor results in better metabolic profiles i think satiety has a lot to do with this
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
it blocks cb1 the cannabinoid one receptor and you know that this makes me very suspicious that products of linoleic acid breakdown specifically anandamide and 2ag as has been shown in animal models could be activating that cb1 receptor
there's another nambi paper where they showed that the oleic acid prevents the breakdown of circulating cannaboids um and so and so the cannaboids are endogenous molecules that we make that hit our cannaboid receptors and kind of can give you the munchies right if you have too many of these cannaboids and and the the oleic acid is preventing the breakdown of the cannaboids