Peter Attia· MD
this pathway is responsible for vascular smooth muscle proliferation coronary artery vascular smooth muscle proliferation thereby making your coronaries tighter and less likely to be able to vasodilate when they need to thus increasing risk for heart attack it also causes cell division because insulin is a mitogen it causes cells to divide well if it causes your breast cell to divide you might end up with breast cancer and so hyperinsulinemia is associated with all of the chronic metabolic diseases we know about because of this second phenomenon that insulin does not just lower in glucose which it does is a sidelight of storing energy but in fact because it causes both inflammation and cell division