Metformin can lower insulin levels and inflammatory factors, potentially by fixing cellular aging.

“I think at the end the lower insulin levels the low inflammatory are not necessarily a direct effect and that's why we're we're fighting all the time about what metformin is doing because you measure lots of things but the things you're measuring her because aging was fixed and once aging is fixed then there's a whole ham or dynamic readjustment or whatever you want to call it and then you're measuring that everything and this is not only typical to metformin this is with rapamycin with resveratrol”