The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Now, of course, that's counterintuitive because we know it activates AMPK. So I probably have to sit down and think about this. But we do know metformin inhibits complex one. And we know that complex one turns NADH to NAD, which makes me wonder, is it possible that metformin would impair DNA repair through that mechanism by reducing substrate? I have no idea.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.