Metformin may exert anti-cancer benefits by interfering with aspartate degradation, a potential rate-limiting step in cancer metabolism.

“did you see that paper that came out in nature two days ago about aspartate being a rate limiting step in cancer metabolism in the mitochondria I didn't see that I haven't Bob and I were just talking about it today it's interesting because the paper was part of it was written through a lens of hey this might be how metformin can exert some of its anti-cancer benefits by interfering with aspartate I think it was interfering with degradation of aspartate but again I haven't read the paper yet just sort of the abstract but it was yet another like I didn't know that”