when you do that what is that telling the cell by inhibiting that the cell's readout is what physiologically three things first that battery that you're talking about that generates to make ATP a less charge less charged so then what happens ATP goes down ATP goes up there's a kindness called ampk kinase ampk is the MP kinase and same PK it gets activated and in part that enzyme is activated is a signal that says I'm not fed enough right right and one of the major things it does is it promotes etaf adji mmm my favorite your favorite right it's one of the dominant things it does that's why when ampk gets activated we get another little benefit Allah rapamycin z' effect on mTOR which is it says hey man I'm telling you from a glycolytic standpoint or from an ox Foss standpoint energy is low shut things down right nutrients are scarce right