Peter Attia· MD
metformin yes rapamycin no
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
metformin yes rapamycin no
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
you don't personally take these agents yet i'm guessing no and that says something right i mean that do you do you think of yourself as a particularly risk-averse individual or is that just sort of the way you you you think about things and unintended consequences i like data i want the data to decide what i'm going to do so i want to generate the data if i i would want to be in a clinical trial where there's data generated to say what is this doing so that we learn
i'll just share personally my experience i've taken both together
now the reason we decided to do this as a podcast with both near and joan as guests was because of course there were many overlaps between rapamycin and metformin not just in terms of longevity but also of recent note their potential for reducing the risk of saros cov2 infection or other infections and of course covet 19 morbidity and we speculate on those things to a great deal
nope i don't feel anything that i can that i can comment on